Water For Injection System (WFI)

 BIOCELL WFI water for injection equipment & system adopts an advanced three-stage separation process of steam and water, and the quality of produced water meets the standards of Chinese, American, and European Pharmacopoeia, GMP, FDA, and other certification requirements; Humanized design, modular installation, small floor area, stable operation, one button start, simple operation and maintenance, high efficiency, and energy saving.

 

DIFFERENT TYPES OF WFI SYSTEM

Multi-Effect Distiller

Single Effect Distiller

Electrically Heated Distiller

Combis TWO in ONE

WFI Cold Generation System

Multi-Effect Distiller

 

The multi effect distilled water machine is designed and manufactured according to the industry standard YY0229 Multi effect Distilled Water Machine. All parts are made of 304 and 316L stainless steel. The distilled water produced is of high purity and pyrogen free, and fully complies with the quality indicators of water for injection in the Pharmacopoeia of the People's Republic of China (2020). It is the ideal equipment for manufacturers of various blood products, injections, infusion, biological antibacterial and other drugs and manufacturers of drinking distilled water.

 

Single Effect Distiller

The single effect distilled water machine is a small distillation unit designed to meet the needs and budgets of growing organizations interested in developing new products. Up to 300L of water

for injection can be produced per hour.

 

Electrically Heated Distiller

The electric heating distilled water machine uses purified water as raw water and electric energy (converted into heat energy) as heating source, and the distilled water produced completely meets the quality indicators of "water for injection generation" in the Chinese Pharmacopoeia 2020.

 

Combis TWO in ONE

This model is applicable to the production conditions of producing pure steam disinfection on one side and water for injection on the other side. Disinfection and water preparation can operate simultaneously and independently without mutual interference. It is a production equipment that can operate in dual synchronization, and water production and steam production do not affect each other.

 

WFI Cold Generation System

The production capacity of cold water for injection (full membrane method) is 200-30000L/H, which is used in medical, daily chemical and other industries. It uses terminal ultrafiltration technology to remove heat source impurities on the basis of traditional purified water, so that the endotoxin index is lower than the standard requirements of "water for injection" in the pharmacopoeia, providing a new, stable and reliable choice for related enterprises to prepare water for injection.

 

WHAT IS THE WORKING PRINCIPLE OF WFI SYSTEM?

The wfi generation system has low investment cost, low operation, and energy consumption, and can operate continuously and dynamically. Under the condition of low-temperature storage and turbulence, it can effectively control the microbial breeding risk of the whole system and can realize large-scale water supply.

 

water for injection system

 

What is the working principle of WFI system?

WHAT IS WATER FOR INJECTION?

Water for injection (WFI) is a high-purity water used in the pharmaceutical industry for the preparation of injectable medications and medical devices. WFI system must meet strict quality standards to ensure that it is free from microbial and chemical contaminants that could harm patients.

 

What Is Water for Injection Used For

The water for injection generation system is used as a diluent or solvent for drugs that are administered by injection, including intravenous, intramuscular, and subcutaneous injections. It is also used as a component in the preparation of medical devices, such as wound dressings and contact lenses.

 

The high purity of WFI is critical to ensure the safety and efficacy of the medications and devices prepared with it. Even trace amounts of contaminants can cause adverse reactions in patients, such as infections or allergic reactions. Therefore, water for injection systems is subject to strict quality standards and is regularly tested to ensure that it meets the required specifications.

 

Wfi Generation Process

The generation of water for injection (WFI) system in the pharmaceutical industry typically involves a multi-step process to remove impurities and contaminants from the feed water. The WFI generation process may include the following steps:

 

Pretreatment: The first step is to remove large particles and suspended solids from the feed water. This may be accomplished by using filters, such as sand or cartridge filters.

 

Reverse osmosis (RO): The pretreated water is then passed through a reverse osmosis membrane, which removes dissolved salts and other impurities. RO uses high pressure to force water through a semi-permeable membrane that separates the water from dissolved salts and other contaminants.

 

Cold WFI by Membrane Methods

When using the whole membrane method to prepare cold water for injection, special attention should be paid to the design of regular sanitary treatment of the system. Cold process is always more susceptible to microbial contamination than traditional hot distillation. The cold WFI power generation equipment shall be cleaned regularly, preferably by thermal disinfection.

 

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